Tommy Makinson is set to make his England debut when they face New Zealand on Sunday.
The winger has been selected in Wayne Bennett’s team alongside Jonny Lomax, James Roby and Mark Percival.
Luke Thompson sadly misses out.
Saints has five representatives in England’s 19-man squad with James Graham also coming through the Academy system here.
Saints Academy Head Coach Derek Traynor said: “The club is really proud to provide six players for the England squad.
“It shows our system’s consistency over the years to produce players like James Roby and James Graham, right through to Luke Thompson.
“James Graham was with the club from 12 years of age whilst James Roby signed pro terms with us in our Foundation Academy.
“Mark Percival has been with us from 14, Tommy signed into our Academy from St Judes and Lomax and Thompson have been here since the age of 11.
“We will carry on working hard towards developing future first team players and setting high standards so they can progress to becoming full internationals.
“We believe there are already a number in our system that will eventually reach these same high standards and represent their country.”
Graham will make his 40th England appearance almost 10 years to the day since his first England appearance against France in June 2008.
Of the current squad, James Roby and Sam Burgess also played in that game.
Hull FC’s Jake Connor will also make his debut.
John Bateman (Wigan Warriors, Bradford Dudley Hill) Caps: 12 (4 tries)
Sam Burgess (South Sydney Rabbitohs, Dewsbury Moor) Caps: 22 (8 tries)
Thomas Burgess (South Sydney Rabbitohs, Dewsbury Moor) Caps: 20 (2 tries)
Jake Connor (Hull FC, Siddal) Caps: 0
James Graham (St George Illawarra Dragons, Blackbrook) Caps: 39 (3 tries)
Ryan Hall (Leeds Rhinos, Oulton Raiders) Caps: 37 (34 tries)
Chris Hill (Warrington Wolves, New Springs Lions) Caps: 25
Jonny Lomax (St Helens, Orrell St James) Caps: 6
Tommy Makinson (St Helens, Wigan St Judes) Caps: 0
Jermaine McGillvary (Huddersfield Giants, Deighton Juniors) Caps: 12 (12 tries)
Sean O’Loughlin (c) (Wigan Warriors, Wigan St Patricks) Caps: 23 (5 tries)
Mark Percival (St Helens, Halton Farnworth Hornets) Caps: 4 (2 tries)
Stefan Ratchford (Warrington Wolves, Wigan St Patricks) Caps: 4 (2 tries)
James Roby (St Helens, Blackbrook) Caps: 31 (6 tries)
Scott Taylor (Hull FC, Skirlaugh) Caps: 3
Elliott Whitehead (Canberra Raiders, West Bowling) Caps: 15 (4 tries)
Gareth Widdop (St George Illawarra Dragons, Kings Cross) Caps: 27 (7 tries, 65 goals, 1 field goal)
England v New Zealand will be played at the Sports Authority Field at Mile High, Denver on Saturday June 23 and fans in the UK can watch live from 9.10pm (BST) on BBC Two.